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                      SECURITIES AND EXCHANGE COMMISSION
                            Washington, D.C.  20549

                                 SCHEDULE 13G
                                (Rule 13d-102)


             INFORMATION TO BE INCLUDED IN STATEMENTS FILED PURSUANT
           TO RULES 13d-1(b)(c), AND (d) AND AMENDMENTS THERETO FILED
                           PURSUANT TO RULE 13d-2(b)

                         (Amendment No.            )(1)


                           Alexion Pharmaceuticals, Inc.
--------------------------------------------------------------------------------
                                (Name of Issuer)


                             Common Capital Stock
--------------------------------------------------------------------------------
                         (Title of Class of Securities)


                                    01535110
--------------------------------------------------------------------------------
                                 (CUSIP Number)


  (1)The  remainder  of this  cover  page  shall be filled  out for a  reporting
     person's  initial  filing on this form with respect to the subject class of
     securities,  and for any subsequent amendment containing  information which
     would alter the disclosures provided in a prior cover page.

     The  information  required in the remainder of this cover page shall not be
deemed to be "filed"  for the purpose of Section 18 of the  Securities  Exchange
Act of 1934 or otherwise  subject to the  liabilities of that section of the Act
but  shall be  subject  to all other  provisions  of the Act  (however,  see the
Notes).





<PAGE>

CUSIP No. 01535110                  13G                    Page   2 of  5  Pages


________________________________________________________________________________
1.   NAME OF REPORTING PERSONS  The Kaufmann Fund, Inc.  TIN# 13-2605091
     I.R.S. IDENTIFICATION NO. OF ABOVE PERSONS (ENTITIES ONLY)



________________________________________________________________________________
2.   CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*
                                                                 (a)  [_]
                                                                 (b)  [_]

________________________________________________________________________________
3.   SEC USE ONLY



________________________________________________________________________________
4.   CITIZENSHIP OR PLACE OF ORGANIZATION  United States



________________________________________________________________________________
  NUMBER OF    5.   SOLE VOTING POWER 837,300
                    
   SHARES           
               _________________________________________________________________
BENEFICIALLY   6.   SHARED VOTING POWER  N/A
                    
  OWNED BY          
               _________________________________________________________________
    EACH       7.   SOLE DISPOSITIVE POWER 837,300
                    
  REPORTING         
               _________________________________________________________________
   PERSON      8.   SHARED DISPOSITIVE POWER  N/A
                    
    WITH            
________________________________________________________________________________
9.   AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON 837,300



________________________________________________________________________________
10.  CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES*

                                                                          [_]

________________________________________________________________________________
11.  PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9)  7.41%



________________________________________________________________________________
12.  TYPE OF REPORTING PERSON*  IV



________________________________________________________________________________
                     *SEE INSTRUCTIONS BEFORE FILLING OUT!


<PAGE>


CUSIP No. 01535110                  13G                    Page 3   of 5   Pages


________________________________________________________________________________
Item 1(a).  Name of Issuer: Alexion Pharmaceuticals, Inc.



________________________________________________________________________________
Item 1(b).  Address of Issuer's Principal Executive Offices:
25 Science Park, Suite 360, New Haven CT 06511


________________________________________________________________________________
Item 2(a).  Name of Person Filing: The Kaufmann Fund, Inc.



________________________________________________________________________________
Item 2(b).  Address of Principal Business Office, or if None, Residence:
140 E. 45th Street, 43rd floor, New York, NY 10017


________________________________________________________________________________
Item 2(c).  Citizenship: United States



________________________________________________________________________________
Item 2(d).  Title of Class of Securities: Common Capital Stock



________________________________________________________________________________
Item 2(e).  CUSIP Number: 48625010



________________________________________________________________________________
Item 3.     If This Statement  is Filed  Pursuant to  Rule 13d-1(b), or 13d-2(b)
            or (c), Check Whether the Person Filing is a:

     (a)  [_]  Broker or dealer registered under Section 15 of the Exchange Act.

     (b)  [_]  Bank as defined in Section 3(a)(6) of the Exchange Act.

     (c)  [_]  Insurance  company as defined in Section 3(a)(19) of the Exchange
               Act.

     (d)  [X]  Investment  company  registered under Section 8 of the Investment
               Company Act.

     (e)  [_]  An investment adviser in accordance with Rule 13d-1(b)(1)(ii)(E);

     (f)  [_]  An employee  benefit plan or endowment  fund in  accordance  with
               Rule 13d-1(b)(1)(ii)(F);

     (g)  [_]  A parent  holding  company or control  person in accordance  with
               Rule 13d-1(b)(1)(ii)(G);

     (h)  [_]  A savings  association  as defined in Section 3(b) of the Federal
               Deposit Insurance Act;

     (i)  [_]  A  church  plan  that  is  excluded  from  the  definition  of an
               investment  company  under  Section  3(c)(14)  of the  Investment
               Company Act;

     (j)  [_]  Group, in accordance with Rule 13d-1(b)(1)(ii)(J).


     If this statement is filed pursuant to Rule 13d-1(c), check this box.   [_]



<PAGE>


CUSIP No. 01535110                  13G                    Page 4   of  5  Pages


Item 4.  Ownership.

     Provide  the  following  information  regarding  the  aggregate  number and
percentage of the class of securities of the issuer identified in Item 1.

     (a)  Amount beneficially owned: 837,300


     (b)  Percent of class: 7.41%


     (c)  Number of shares as to which such person has:

          (i)   Sole power to vote or to direct the vote 837,300             ,


          (ii)  Shared power to vote or to direct the vote    N/A             ,


          (iii) Sole power to dispose or to direct the disposition of 837,300


          (iv)  Shared power to dispose or to direct the disposition of N/A



________________________________________________________________________________
Item 5.  Ownership of Five Percent or Less of a Class.  
If this statement is being filed to report the fact that as of the date hereof
the reporting person has ceased to be the beneficial owner of more than five
percent of the class of securities, check the following (  )



________________________________________________________________________________
Item 6.  Ownership of More Than Five Percent on Behalf of Another Person. N/A



________________________________________________________________________________
Item 7.  Identification and Classification of the Subsidiary Which Acquired the
         Security Being Reported on by the Parent Holding Company.  N/A



________________________________________________________________________________
Item 8.  Identification and Classification of Members of the Group.  N/A



________________________________________________________________________________
Item 9.  Notice of Dissolution of Group.  N/A



________________________________________________________________________________
Item 10.  Certifications.

     (a)  The  following  certification  shall be included if the  statement  is
          filed pursuant to Rule 13d-1(b):

          "By signing  below I certify  that,  to the best of my  knowledge  and
          belief, the securities referred to above were acquired and are held in
          the ordinary course of business and were not acquired and not held for
          the  purpose  of or with the effect of  changing  or  influencing  the
          control of the issuer of the  securities and were not acquired and are
          not held in  connection  with or as a participant  in any  transaction
          having such purpose or effect."


 
<PAGE>


                                    SIGNATURE

     After  reasonable  inquiry and to the best of my  knowledge  and belief,  I
certify that the information  set forth in this statement is true,  complete and
correct.



                                                    August 20, 1999
                                                        (Date)



                                                  Anthony W. Toogood
                                                      (Signature)



                                                     Vice President
                                                      (Name/Title)